Supporting prostate cancer research

Weight loss programme for prostate cancer patients.

Ms Rebekah Wilson, Exercise Medicine Research Institute at Edith Cowan University

Androgen deprivation therapy (ADT) is a common treatment for prostate cancer. One of the many possible side effects of this treatment is weight gain. Lifestyle changes utilising exercise and diet have been demonstrated as safe and result in improved health, physical function, and quality of life for cancer patients. The purpose of this study is to assess the efficacy of an exercise and diet programme designed to induce weight loss.

The study timeline will include a 6-week waiting period, followed by a 3-month exercise and diet intervention, and a further 3-month home-based programme. The participant will be required to attend a series of testing days during this time including assessment of body composition (fat, muscle, and bone mass), resting metabolic rate, blood and inflammatory markers, physical function (muscular strength, aerobic fitness), dietary monitoring, and quality of life.

The 3-month exercise and diet intervention will involve completing 3 supervised exercise sessions a week for 12 weeks and attending 3 nutritional counselling sessions during this time. The exercise will include individually prescribed resistance and aerobic training accumulating 300 minutes/week (45 minutes/day). The nutrition component will also be individually prescribed and focus on decreasing portion sizes and advise on carbohydrate, fat, and protein consumption.

Ethics approval has been granted by Edith Cowan University Human Research Ethics Committee.

Who is this study for?

You may be eligible for this study if you:

  • Be currently receiving androgen deprivation therapy (hormone blocking therapy) as part of your prostate cancer treatment plan;
  • Have no bone metastasis (tumours spread to bones)
  • Have no secondary cancer diagnosis
  • Have no medical conditions that may prevent you completing an exercise programme.
  • Comfortably walk 400 m.

You would need to meet all the above criteria to be involved in this study.

This study is currently recruiting participants.

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